Tuesday, June 27, 2006

Vioxx: NEJM Corrects Risk Study

The Vioxx APPROVe study contained math errors that wrongly showed the risks changed over time, the New England Journal of Medicine has informed. The NDJM corrected the March 2005 study that led to the drug's withdrawal from the market to show the risks do not, as originally shown, greatly increase after 18 months.

The mistake was significant enough to change some of the conclusions of the trial -- including the eighteen month cutoff.

Sources include the NEJM site and Reuters.com