Monday, March 31, 2008

Celebrex a Risk at Higher Doses (400 mg+)

If you type in Celebrex at the top of this blog and hit enter, you'll find a number of posts on that drug.

From pharmalot.com and other sites, this 'news' which has been discussed for more than two years:

Patients taking the largest dose of 400 mg twice a day tripled their chance of a heart attack or stroke, compared with people taking a placebo, according to a study presented today at the American College of Cardiology meeting. The study confirms earlier concerns that prompted the FDA three years ago to warn that Celebrex and other painkillers, including ibuprofen and naproxen, should be prescribed at the lowest dose possible.

The 200 milligram dosage is the most commonly prescribe dose of the medication.

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