Orlistat, which goes by the prescription brand name Xenical and the over-the-counter name Alli, can cause “severe toxicity” to major internal organs, says a recent study. .
The research results obtained by pharmacology professor Bingfan Yan
were worrying enough that he immediately reported the results to the
FDA, which approved orlistat in 1999.
Liver and kidney damage are serious enough, but the report had another finding that orlistat’s metabolic
action reduces the effectiveness of many medications, including
life-saving cancer treatments. In fact, the researchers reported that
cancer cells multiplied faster under the influence of orlistat. Orlistat
also boosts the anti-clotting effects of aspirin, raising the risk of
bleeding both internal and external.