Treanda and Stevens Johnson Syndrome

The cancer drug Treanda, in combination with another therapy, may have caused two people taking it to develop a serious skin condition known as Stevens Johnson Syndrome and one has died.


The patients developed a severe form of the condition known as toxic epidermal necrolysis, which is characterized by a blistering and peeling of the top layer of skin, causing it to peel off, leaving damaged areas which can become infected.

Both patients were also taking a drug called allopurinol, which is often used in patients taking chemotherapy to lower high levels of uric acid in the body. The drug is already known to be associated with Stevens Johnson Syndrome/toxic epidermal necrolysis.

Source here.