People treating with methadone have died or suffered life-threatening side effects according to the FDA.
Overdoses of the increasingly popular narcotic can cause slow or shallow breathing and dangerous changes in heartbeat that patients might not feel.
In 2003, methadone was listed as a cause of 2,452 unintentional poisoning deaths in the United States, up from 623 in 1999, according to the National Center for Health Statistics.
According to most reports, prescribing methadone is complex. Methadone should only be prescribed for patients with moderate to severe pain when their pain is not improved with other non-narcotic pain relievers.
For more go here. You can find the FDA Advisory here.